Alkaline phosphatase is an enzyme found in the different parts of your body like the liver, bones, and intestines. It plays a vital role in maintaining your overall health.
However, when the levels of alkaline phosphatase become elevated, it could be a sign of an underlying health issue. And sometimes you eat something that raises your ALP and you don’t realize it.
So in today’s blog post, we will explore the causes of high alkaline phosphatase and focus on the diet for managing your ALP. Specifically, we will discuss 7 foods that are best avoided if alkaline phosphatase levels are high, and provide insights into healthier alternatives.
What Is Alkaline Phosphatase?
Alkaline phosphatase (ALP) is a hydrolase enzyme found in numerous tissues throughout the body. It removes phosphates from various substances like proteins, nucleotides, and alkaloids.
The highest concentrations of ALP are present in the cells that comprise bone and the liver. But it also exits in other parts of the body like:
- Your kidneys.
- Your bile duct.
- Your intestines.
- The placenta in pregnant people.
Elevated levels of ALP in the blood can often indicate liver disease or bone disorders.
Interestingly, children and adolescents usually have higher levels of ALP than adults due to bone growth. Doctors can detect ALP levels through a simple blood test, often part of a routine liver panel.
In healthy adults, ALP levels typically range from 20 to 140 units per liter (U/L). If ALP levels are high, it may sign of medical conditions like liver disease, bone disorders, or certain types of cancer.
On the other hand, if your ALP levels are low it could indicate malnutrition or a lack of certain vitamins. So, it’s important to keep your ALP level balanced for good overall health.
Also, it’s important to note that certain medications, smoking, and even some foods can contribute to increased ALP levels. For this reason, following to a carefully planned diet can be a significant factor in managing ALP levels.
What causes high levels of alkaline phosphatase?
There are many factors that cause high levels of alkaline phosphatase. These include liver diseases like hepatitis, cirrhosis, gallstones, or liver cancer.
Bone disorders like Paget’s disease, osteomalacia, or hyperparathyroidism can also cause elevated ALP levels. Furthermore, certain cancers that have spread to the bones or liver can cause a rise in ALP.
In addition to these conditions, high levels of ALP can also be a result of a blockage in the bile ducts or an infection in the gallbladder [1]. Pregnant women may also experience increased ALP levels, especially in the third trimester, due to increased placental activity.
Certain medications, including birth control pills, some antibiotics, and certain painkillers, can also raise ALP levels. This is why it’s important to inform your healthcare provider about any medications you are currently taking.
Lastly, consuming excessive amounts of alcohol or fatty foods can cause higher ALP levels. We will shortly discuss what should you eat or avoid to fully maintain your ALP levels.
But before you move next it is important to understand the level at which Alkaline Phosphate becomes dangerous and causes complications. Here’s how you can check it.
What Level Of Alkaline Phosphatase Is Dangerous? Complete Guide
Diet for High Alkaline Phosphatase
Diet plays a major role in alkaline phosphate levels. But keep in mind that it’s not the only factor you should rely on. There are plenty of other lifestyle changes that you should implement to keep your ALP levels under control.
When it comes to diet, here are 7 foods that you should avoid if your ALP levels are high:
7 Foods to Avoid If Alkaline Phosphatase Is High
1. Zinc-Rich Foods
Zinc is a mineral that plays a vital role in the body’s immune system, cellular growth and division, and wound healing. However, when consumed in excess, it can interfere with ALP levels.
A study examined the effects of taking 50 mg of zinc orally on bone health in healthy male volunteers. Zinc was studied to see how it affects bone turnover. The results showed that after 12 weeks of zinc treatment, there was a significant increase in the activity of total alkaline phosphatase (ALP) which is an important marker for bone formation.
Foods high in zinc include:
- Oysters
- Beef
- Crab and Lobster
- Pork
- Chicken
- Baked beans
- Pumpkin seeds
- Cashews
- Chickpeas
- Yogurt
- Cashew
- Turkey and fruits
- Baked beans
2. High-Fat Meal
Foods high in fat can increase the load on your liver, which in turn can contribute to increased ALP levels.
These include fried foods, processed meat, and baked goods. Studies show that people with blood type B or O who are secretors may be more susceptible to changes in ALP activity after consuming a high-fat meal. The impact of this effect tends to be highest 3 to 6 hours post-meal. Here’s a list of high-fat foods you might want to avoid:
- Fast food
- Fried food like french fries and fried chicken
- Pastries, cakes, and cookies
- Sausages, hot dogs, and cured meats
- Ice cream
- Cheese
- Butter and margarine
- Pizza
- Burgers
- Creamy sauces and dressings
It’s better to opt for foods with healthy fats like avocados, fish, nuts, and seeds, which can contribute to overall health without negatively affecting your ALP levels.
3. Processed Foods
Processed foods and especially those high in sodium or preservatives can cause inflammation in the body and put extra stress on your liver, leading to increased ALP levels.
These include canned foods, packaged meals, instant noodles, processed meats, and certain types of cheese.
Additionally, certain studies have shown a correlation between high consumption of processed foods and raised liver enzymes. Here’s a list of processed foods you should limit or avoid:
- Processed meats like sausages, hot dogs, and bacon
- Packaged snacks like chips and cookies
- Instant noodles and soups
- Frozen dinners
- Canned vegetables and fruits
- Boxed meals and mixes
- Processed cheeses
It’s recommended to consume fresh, whole foods as much as possible. Fresh fruits and vegetables, lean meats, whole grains, and legumes are all excellent choices that can contribute to overall health and help regulate ALP levels.
4. Foods higher in phosphorus
Nowadays, many people are curious about which foods to avoid if their alkaline phosphatase is high. The answer lies in phosphorus. This amazing mineral makes up about 1% of our body weight and is crucial for the health of our cells and bones.
So, a high intake of phosphorus can lead to an increase in ALP activity. Foods high in phosphorus include:
- Dairy products like milk, cheese, yogurt, and ice cream
- Processed foods like frozen meals and fast food
- Red meat and poultry
- Fish, especially canned or processed
- Nuts and seeds
- Beans, lentils, and other legumes
- Whole grains and bran cereals
- Dark-colored sodas
Limiting your intake of these foods and opting for low-phosphorus alternatives can help manage your ALP levels.
5. High-Fructose Foods
Consuming too much fructose can raise the risk of liver disease, leading to higher levels of Alkaline Phosphatase.
Consuming large quantities of high-fructose foods and beverages can cause non-alcoholic fatty liver disease (NAFLD), a condition characterized by excess fat build-up in the liver.
A study has shown that a diet high in fructose can increase ALP levels, as it causes an increase in liver fat and inflammation. High-fructose foods to avoid include:
- Soda and other sweetened beverages
- Candy and sweets
- Sweetened cereals
- Processed foods
- High-fructose fruits like apples, grapes, watermelons, pears, and mangoes
It is healthier to choose foods with naturally occurring sugars, like fresh fruits and vegetables, and to limit the intake of foods with added sweeteners.
6. Certain Herbal Supplements
Some herbal supplements may negatively affect the liver which causes rise in ALP levels. Supplements like kava, comfrey, green tea extract, and pennyroyal oil have all been linked to liver damage in some cases.
For instance, a study has shown that the use of the herbal supplement kava can cause hepatotoxicity, which is evident through elevated levels of liver enzymes including ALP. Be cautious with the following supplements:
- Kava
- Comfrey
- Green tea extract
- Pennyroyal oil
Do not take any supplements without the recommendation of your doctor, especially if you have elevated ALP levels or other liver-related health issues. Always choose high-quality, reputable supplement brands to ensure safety and efficacy.
7. Foods that are high in Vitamin B-12
Vitamin B-12 which is also called cobalamin. It is important for making DNA, red blood cells, and keeping the nervous system working well.
However, an excess intake may cause complications like imbalances in homocysteine levels, which are related to heart disease and stroke. Certain foods are notably high in Vitamin B-12, and these include:
- Fish like salmon and tuna
- Shellfish such as clams and oysters
- Beef and beef liver
- Eggs
- Dairy products like milk, cheese, and yogurt
- Fortified breakfast cereals
These products and food items can increase the production of ALP which may cause problems with bone marrow.
So, it’s wise to limit the intake of these Vitamin B-12 rich foods. If you’re worried about your Vitamin B-12 levels, seek guidance from your doctor or a dietitian for personalized advice.
What food should I eat to lower alkaline phosphatase?
When it comes to alkaline phosphatase levels, there isn’t a specific diet to raise them. However, you should be concerned about low alkaline phosphatase levels and the potential impact of your diet on those numbers. If your blood test shows low alkaline phosphatase, it could be due to a diet lacking in nutrients.
By consuming foods that meet these criteria, you can promote a healthier balance.
1. Fruits and Vegetables: These are packed with antioxidants which are beneficial for liver health. Green leafy vegetables like spinach, kale, and broccoli can help in flushing out toxins from the body.
2. Lean Proteins: Chicken, turkey, tofu, and fish are great sources of lean protein which help in the repair and regeneration of liver cells.
3. Whole Grains: Foods like brown rice, oatmeal, fortified breakfast cereals, and whole-grain bread are packed with fiber. They help in your digestion, regulate blood sugar levels, and promote liver health.
4. Healthy Fats: Avocados, olives, and nuts are ideal sources of healthy fats. These fats help reduce inflammation and are beneficial for liver health.
5. Spices: Turmeric and milk thistle are known for their liver-cleansing properties. Including these spices in your diet can help maintain a healthy liver and lower ALP levels.
6. Hydration: Adequate hydration is very important for liver health. It helps in maintaining the overall functions of the body, including the detoxification process carried out by the liver.
Remember, while diet plays a significant role in maintaining optimal ALP levels, it’s equally important to avoid alcohol, quit smoking, and engage in regular physical activity.
Must Read: What Level of Alkaline Phosphatase is Dangerously Low?
What are some other activities that can help keep the alkaline phosphatase levels in check?
As we said diet in not the only factor to consider when managing alkaline phosphatase levels. Here are some other activities that can help:
1. Increased exposure to sunlight: Vitamin D is very important in regulating ALp levels. Sunlight is a great free source of vitamin D for our body. It is essential for healthy bones and a strong immune system. Make sure to get at least 20 minutes of sun every day and try to reduce your ALP levels.
2. Stress Management: Chronic stress can have a detrimental effect on your liver health. Techniques like meditation, yoga, and deep breathing exercises can help manage stress levels and maintain a healthy liver.
3. Regular Health Check-ups: It is essential to have regular health check-ups to monitor your liver function and ALP levels. Regular blood tests can help detect any abnormalities early and allow for prompt treatment.
4. Avoiding Harmful Substances: Limiting exposure to harmful substances like pesticides, heavy metals, and certain drugs can help protect your liver and keep ALP levels stable.
5. Healthy Sleep Patterns: Adequate sleep is crucial for various bodily functions, including liver health. A lack of quality sleep can cause disorders like fatty liver disease. Aim for 7-9 hours of sleep per night for optimal health.
6. Regular Exercise: Engaging in regular physical activity, like walking, jogging, cycling, or aerobic exercises, can help regulate liver function and manage ALP levels. The American Heart Association recommends at least 150 minutes of moderate-intensity exercise or 75 minutes of vigorous exercise per week.
What level of alkaline phosphatase is concerning?
The levels of Alkaline Phosphatase (ALP) can vary greatly depending on age, gender and individual health conditions.
According to NIH, the normal level of ALP in human blood is usually between 25 and 100 IU/L. However, when the ALP concentration goes beyond 300 IU/L it may be a cause for concern.
This high level of ALP causes different diseases like liver diseases, liver cancer, bone disease, hepatitis, kidney cancer, and osteoblastic bone cancer.
In contrast, low ALP levels can also be problematic. If your Alkaline Phosphatase levels consistently drop below 20 U/L, it is considered dangerously low.
Having consistently low levels can cause serious health problems, like certain types of anemia, not getting enough protein, or overall malnutrition which can all negatively impact your health.
Why is it important to control high alkaline phosphatase levels?
Keeping your Alkaline Phosphatase (ALP) levels in check is important for maintaining a healthy body and overall well-being. When ALP levels are too high, it could be a sign of serious health issues like liver disease, blocked bile ducts, or certain bone disorders.
High levels of ALP can cause increased bone density or overly active bone formation. In the context of liver diseases, High ALP levels might imply damage or stress to the liver cells, potentially causing cirrhosis or hepatitis.
Additionally, studies have shown that elevated ALP levels are linked with increased mortality rates in people with cardiovascular conditions. Hence, it is highly recommended to regularly monitor and manage ALP levels as part of a complete healthcare strategy.
Keeping a balanced diet, regular exercise and routine health check-ups are effective ways to maintain healthy ALP levels.
Conclusion
In conclusion, maintaining balanced Alkaline Phosphatase (ALP) levels is a basis of overall health and well-being. Through a combination of a nutrient-dense diet, regular physical activity, stress management, and routine health check-ups, individuals can effectively manage their ALP levels.
It’s essential to remember that prolonged high or low ALP levels can be indicative of serious health issues.By taking quick actions, people can reduce potential health risks, which not only benefits their liver and bones but also their overall well-being.
FAQ
What food can increase alkaline phosphatase levels?
Foods like whole grain bread, fortified cereals, and certain fruits and vegetables can potentially help increase Alkaline Phosphatase (ALP) levels. Consuming healthy fats like those found in avocados, olives, and nuts can also be beneficial.
Does alkaline phosphatase increase appetite?
Alkaline Phosphatase itself does not directly increase appetite. However, high levels of ALP may be associated with certain health conditions that can affect appetite. Any changes in appetite should be discussed with a healthcare provider.
How to lower alkaline phosphatase levels naturally?
Lowering alkaline phosphatase (ALP) levels naturally can be achieved through several methods. Enhancing your diet with foods rich in vitamin D and B-12, like fish and dairy products, can be beneficial. To manage ALP levels, you can do regular exercise, try stress-relief methods like yoga or meditation, maintain a healthy sleep routine, and stay away from harmful substances.
How to lower alkaline phosphatase levels in the liver?
You need a healthy lifestyle for lower alkaline phosphatase levels in the liver. This includes eating a diet rich in fruits, vegetables, and lean proteins, exercising regularly, reducing alcohol consumption, and avoiding exposure to harmful substances. Additionally, regular check-ups with your doctor can help monitor liver health.