How Long After Taking AZO Can I Breastfeed?

How Long After Taking AZO Can I Breastfeed

After having a baby, many new moms deal with health issues like urinary tract infections (UTIs) or pain. A common solution for temporary relief is AZO (Phenazopyridine).

But, for moms who are breastfeeding, it’s really important to know how this medication might impact their baby. This is especially the case with medicines you can buy without a prescription, like AZO. They don’t always come with clear instructions on if it’s safe to use while breastfeeding.

In this article, we will explore important considerations, including the pharmacodynamics of AZO, its effects on milk production and quality, and expert recommendations on the timing of breastfeeding post-AZO administration.

What is AZO?

AZO, known chemically as Phenazopyridine, is an over-the-counter medication preferred by many experts for its effectiveness in providing relief from urinary discomfort.

It works as a pain reliever targeting the urinary tract and is commonly used to alleviate symptoms linked with UTIs, like pain, burning, urgency, and frequency of urination.

It’s important to note that while AZO can relieve symptoms, it does not treat the underlying infection; a separate antibiotic treatment is necessary for that purpose.

How AZO Works

When taken, AZO is quickly absorbed by the gastrointestinal tract and begins to exert its effect by concentrating directly in the urine, where it has a local analgesic—or pain-relieving—effect on the mucosa of the urinary tract.

Basically, it helps to calm down any irritation in the bladder and urethra, making you feel a lot more comfortable. Since AZO mainly works in the urinary tract, it doesn’t really mess with the rest of your body, which means fewer side effects.

Side effects of AZO

Although AZO is considered safe for many people, it can cause side effects in some people. Here is a list of known side effects:

  • Orange or red discoloration of urine
  • Stomach cramps
  • Headache
  • Dizziness
  • Nausea

Most of these side effects are relatively mild and tend to resolve on their own. However, if you experience any severe reactions or if the side effects persist, it’s crucial to seek medical advice.

Also Read: How Long Will My Pee Be Orange After Taking Azo?

AZO and Breastfeeding

If you are a new mom, breastfeeding may still be a new and sometimes challenging experience. You want to do everything possible to ensure your baby’s health while also taking care of your own well-being.

It’s still unclear if taking Azo while breastfeeding is safe or not because it could lead to some serious health issues. Azo can cause conditions like hemolytic anemia, sulfhemoglobinemia, and methemoglobinemia, which are especially dangerous for babies. It’s best to avoid Azo when breastfeeding, especially if your baby is younger than 1 month or has a G6PD deficiency.

How long do I have to wait to breastfeed after taking AZO?

As we said earlier, AZO is not very safe for breastfeeding mothers. But, if you have already taken it and are wondering how long you should wait before nursing your baby, the answer is not straightforward.

According to experts, the general recommendation is to wait at least 2 days after taking AZO before breastfeeding. This is to ensure that the medication has cleared out of your system and won’t harm your baby.

However, if you are still experiencing symptoms and need to continue taking AZO while breastfeeding, it’s important to discuss this with your healthcare provider. They may recommend alternative pain relief options that are safer for both you and your baby.

Potential Effects of AZO on Breast Milk and the Nursing Infant

  • Milk Discoloration: There is a potential for AZO to cause discoloration of breast milk, much like it can change the color of urine to an orange or red hue. However, clinical data on this is scarce.
  • Limited Studies: Research on the direct effects of AZO on breast milk and nursing infants is limited, leading to cautionary use of the medication by breastfeeding mothers.
  • Potential Risk for Infants: Infants, especially newborns and those under a month old, may be at risk of developing conditions like hemolytic anemia if exposed to substances like AZO through breast milk.
  • Recommendation for Monitoring: If a breastfeeding mother has taken AZO and continues nursing, it is advised to closely monitor the infant for any adverse reactions or unusual symptoms, and consult a healthcare provider immediately if any are observed.

It’s important for breastfeeding mothers to consider these potential effects and consult with their provider for personalized advice.

Related: Why Azo Didn’t Turn My Pee Orange? What’s the Reason

Guidelines for Breastfeeding After Taking AZO

If you do decide to take AZO while breastfeeding, here are some important guidelines to keep in mind:

  • Talk to Your Doctor: Before you take AZO, make sure to talk to your doctor. Don’t just start taking it because you read something online. Your doctor knows what’s best for you and can help you find the safest way to use it.
  • Wait Period: If you’ve taken AZO, adhere to the recommended wait period of at least 2 days before breastfeeding to ensure the medication has sufficiently cleared from your system.
  • Alternative Pain Relief: Explore alternative pain relief methods that are safe for breastfeeding mothers. Your healthcare provider can recommend suitable options.
  • Monitor Your Infant: If you breastfeed after taking AZO, closely monitor your infant for any signs of distress, unusual symptoms, or reactions. Seek medical attention if you notice anything concerning.
  • Stay Hydrated: Increase your fluid intake to help expedite the removal of AZO from your system. Drinking plenty of water is beneficial for both you and your nursing infant.
  • Report Any Side Effects: Should you experience any adverse effects from taking AZO, report them to your healthcare provider immediately.
  • Record Medication Intake: Keep a record of when you took AZO and when you resumed breastfeeding. This information can be valuable for healthcare providers in monitoring both your health and your infant’s well-being.

Factors that might influence the waiting time

Several factors can influence the appropriate waiting time before resuming breastfeeding after taking AZO. These include:

  • Metabolism Rate: Individual differences in metabolism can affect how quickly AZO is processed and eliminated from the body.
  • Dosage Taken: Taking more AZO can make it stay in your body longer before it’s completely gone.
  • Frequency of Medication: How often AZO is taken can also play a role; more frequent use might prolong the presence of the drug in the system.
  • Hydration Levels: Adequate hydration can aid in faster elimination of AZO, as it helps to flush the substance through urination.
  • Body Mass: Your body mass may influence how long it takes to metabolize and eliminate AZO, with variations in body fat and muscle composition playing a role.
  • Breastfeeding Schedule: When you breastfeed around the time you take medicine can affect how much of the medicine residue the baby gets through breast milk.
  • Individual Health Conditions: Pre-existing health conditions, especially those affecting the liver or kidneys, can significantly affect the body’s ability to process and eliminate drugs like AZO.


In conclusion, AZO can really help with urinary discomfort, but moms who are breastfeeding need to be careful because it could be risky for their babies. The main thing to remember is to talk to a doctor before taking AZO or any medicine when breastfeeding.

It’s important to follow advice like waiting at least 2 days to breastfeed after taking AZO and watching your baby closely for any problems. Finding safer ways to ease pain and knowing how drugs can impact breast milk and the baby’s health will help moms take better care of themselves and their babies.


How long to pump and dump after Azo?

The practice of “pump and dump” means using a breast pump to empty your breasts and then discarding the milk. After taking AZO, it’s recommended to wait at least 2 days before breastfeeding again. This means that during these 2 days if you choose to pump and dump to maintain your milk supply and comfort, you should continue this practice until the 2-day waiting period has concluded.’

Can I take Azo yeast plus while breastfeeding?

Taking Azo Yeast Plus when breastfeeding is usually safe. This is because the ingredients in Azo Yeast Plus are generally considered safe for moms who are breastfeeding. But as a precaution, it’s always best to consult with your doctor before taking any medication while breastfeeding.

How long does Azo stay in your system?

Azo (phenazopyridine) doesn’t stay in the body for long. It is typically eliminated within 24 to 48 hours after the last dose, primarily through the kidneys. If your kidneys are working well, Azo takes about 7.35 hours to reduce by half in your blood.

“Blood half-life” means the time it takes for half of Azo to be gone from the blood. So, every 7.35 hours, the amount of Azo in the blood drops by 50%. This shows how quickly and effectively the body can get rid of Azo if the kidneys are healthy.




The information provided in this article is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Don’t ignore professional medical advice or put off seeking it just because of something you read here. Although we aim to offer precise and current information, we do not guarantee its completeness, accuracy, reliability, suitability, or availability for any purpose. Using the information in this document is at your own risk. We are not responsible for any losses or damages caused by our content.

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