How Long Does Nausea Last With Wegovy?

How Long Does Nausea Last With Wegovy

Wegovy is a prescription medication that making waves in the weight loss community. However, like any drug, it isn’t without potential side effects.

Among these, one of the most frequently reported side effects is nausea, which raises the question: “How long does nausea last with Wegovy?”

This article will delve into the specifics of Wegovy-induced nausea, exploring why it occurs, how long it usually lasts, and which effective treatment options are available to ease this discomfort. We aim to provide helpful, easy-to-understand answers to your most-asked questions about Wegovy and its side effects.

Understanding What is Wegovy?

Wegovy, which is also called semaglutide, is a weight loss medication approved by the Food and Drug Administration (FDA) in 2021. Manufactured by Novo Nordisk, it’s an injectable drug that helps overweight or obese adults who also have weight-related medical problems or those who have a body mass index (BMI) of 27 or more.

It’s a glucagon-like peptide-1 (GLP-1) receptor agonist, which works by mimicking the functions of natural hormones in your body to regulate appetite and calorie intake.

This medicine plays an important role in the weight loss industry because of its potential to reduce body weight by an average of 15-20%.

Remember, if you want to manage weight effectively, it is important to combine this medicine with a reduced-calorie meal plan and increased physical activity.

Related: Does United Healthcare cover Wegovy for Weight loss

Wegovy side effects

If you experience any signs of an allergic reaction, seek immediate medical assistance. These signs may include hives, itching, rapid heartbeats, difficulty breathing, or swelling of the face, lips, tongue, or throat.

Wegovy may also cause some serious side effects which include:

  • Nausea
  • Changes in vision
  • Diarrhea
  • Unusual mood swings, thoughts of self-harm
  • Constipation
  • Feeling light-headed, on the verge of fainting
  • Increased heart rate
  • Fatigue
  • Symptoms of a thyroid tumor: shortness of breath, swelling or lump in the neck, difficulty swallowing,
  • Signs of pancreatitis: severe upper abdominal pain that radiates to the back, rapid heart rate
  • Gallbladder issues: pain in the upper abdomen, fever, pale stools, jaundice (yellowing of the skin or eyes)
  • Low blood sugar: headache, sweating, confusion, dizziness, rapid heart rate, jitteriness
  • Kidney problems: swelling, decreased urination, fatigue, shortness of breath

Remember, not every user will experience these side effects, and if you experience persistent or severe side effects, you should contact your doctor immediately.

Related: Does wegovy affect menstrual cycle? Uncover the Truth

How long does Wegovy stay in your system?

The active ingredient(semaglutide) in Wegovy, has a long half-life of approximately one week (7 days). This means if you take the highest dose of 2.4 mg means that approximately half (1.2 mg) will remain in your body after 7 days.

Generally, it takes around five half-lives for a drug to be completely eliminated from your system. Thus, you can expect Wegovy to stay in your system for approximately 35 days, or five weeks, after your last dose.(1)

Why does Wegovy cause nausea?

Why does Wegovy cause nausea

The hormone GLP-1 in the Wegovy, that helps regulate your appetite and calorie intake. This hormone imitation interacts with your digestive system and may slow down stomach emptying after eating.

This slowed digestion can create a sensation of fullness, which may result in feelings of nausea or even vomiting in some people.

Please note, that this side effect is often temporary and usually subsides as your body grows accustomed to the medication. However, if it continues consult with your doctor immediately.

Also Read: Does Blue Cross Blue Shield Cover Wegovy For Weight Loss?

How long does nausea last with Wegovy?

Nausea from Wegovy usually lasts for a short duration. It gradually goes away as your body gets used to the medication. In clinical studies, most people reported that the nausea was mild to moderate and lasted for the first 4 to 6 weeks of treatment but improved over time.

It’s good to talk with your doctor about any prolonged or severe nausea. If the nausea becomes too uncomfortable, your doctor may recommend reducing the dosage temporarily or taking the medication with meals to help lessen this side effect.

Remember, do not stop or change the dosage of Wegovy without consulting your healthcare provider.

Treatment options for nausea while taking Wegovy

If you’re experiencing persistent nausea while taking Wegovy, it’s important to remember that you’re not alone, and there are some steps you can take to relieve these symptoms. Here are some treatment options you can consider:

Eat ginger

Ginger has been used as a natural remedy for nausea for centuries.

It’s not clear yet how ginger exactly treats nausea. However, some experts believe that its active components, gingerol, and shogaol, work directly on the stomach and the brain to reduce feelings of nausea.

There is no agreement on the optimal dosage, but certain studies suggest that consuming 1,500 milligrams of ginger daily may help alleviate nausea.

Over-the-counter medications

Some over-the-counter medications are available that can help relieve nausea. These include dimenhydrinate (Dramamine) or meclizine (Bonine) and bismuth subsalicylate (Pepto-Bismol). Always consult with your doctor before starting any new medication to avoid potential drug interactions.

Peppermint Aromatherapy

Peppermint aromatherapy can also provide relief from nausea.

Studies have shown that the scent of peppermint oil can significantly reduce feelings of nausea and vomiting.

A study with 100 participants found that peppermint essential oil, used alone or with medications, effectively reduces nausea.

According to another study, the use of peppermint oil was found to decrease the frequency of nausea, vomiting, and retching in people receiving chemotherapy.


Nausea can often cause a lack of appetite, which in turn can lead to dehydration if you’re not careful. Some people may also feel worsened nausea in dehydration. So staying hydrated is vital especially if you are feeling nauseous.

If you’re feeling nauseous and vomiting, consider replacing lost fluids with electrolyte-rich options. Some examples include:

  • vegetable broth
  • herbal tea
  • sports drinks
  • mineral water

Plus, sucking on ice chips can help keep your mouth moist and may help to alleviate nausea.

Acupressure or Acupuncture

Acupressure or acupuncture are the ancient Chinese techniques that might provide some relief from nausea caused by Wegovy.

Acupuncture involves inserting very thin needles to stimulate specific points in the body. In contrast, acupressure involves putting pressure on these points instead.

One commonly used point for treating nausea is called the P6 or Neiguan. It’s located on the inside of your arm, around three finger-widths down from your wrist.

One study found that acupuncture at the P6 point has been found to effectively reduce nausea in a variety of contexts, including pregnancy and chemotherapy.

If you’re interested in trying out these methods, it’s advisable to first seek out a certified practitioner. Always inform them about your medications and any medical conditions you have.


Wegovy might cause some side effects, including nausea, as it interacts with your digestive system. Usually, nausea is temporary and subsides as your body adjusts to the drug.

If you’re feeling really nauseous, make sure to reach out to your doctor ASAP. Several over-the-counter drugs, dietary changes, and natural remedies could help manage Wegovy-induced nausea.

Remember, everyone’s body responds differently to Wegovy, and what works for one person may not work for another. So, it’s important to keep your doctor informed about your experiences with the medication.


Is it normal to feel sick after eating on Wegovy?

Yes, it’s common to feel sick after eating while taking Wegovy, especially in the early stages of treatment. This is because of the slowed digestion caused by the medication. It’s usually mild and disappears as your body adjusts to the drug. However, if it persists or is severe, contact your doctor.

How long do the side effects of Wegovy last?

The side effects of Wegovy usually last for the first few weeks of treatment and then slowly decrease. However, this can vary from person to person. If you’re experiencing persistent or severe side effects, it’s important to let your doctor know.

When do Wegovy side effects start?

Side effects from Wegovy can start at some point in the first 2 months of treatment. They’re often most noticeable when you first start the medication or increase your dosage. However, they usually lessen over time as your body gets used to the drug.

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The information provided in this article is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Don’t ignore professional medical advice or put off seeking it just because of something you read here. Although we aim to offer precise and current information, we do not guarantee its completeness, accuracy, reliability, suitability, or availability for any purpose. Using the information in this document is at your own risk. We are not responsible for any losses or damages caused by our content.

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